The high-throughput screening facility provides with access to high-throughput screening and high-content screening instruments for assay development and optimization, as well as a 200,000 compound library covering diverse drug-like molecules, bioactive molecules, clinical and preclinical compounds and natural products, which can be flexibly combined with computer-aided screening. The facility is equipped with instrumentation for liquid handlers, multi-label plate reader, spinning disk confocal microscope, surface plasmon resonance system (SPR), isothermal titration calorimeter (ITC), 10x Genomics, automatic workstation, biochemical analyzer, cell culture room, and other devices characterized by microscale, automation and high throughput, which can provide support for users to conduct rapid activity screening.